I would argue either RAID 5 or ZFS RAIDz1 are inherently unsafe, since recovery would take a lot of read-write operations, and you better pray every one of 4 remaining drives will hold up well even after one clearly failed.
I’ve witnessed many people losing their data this way, even among prominent tech folks (looking at you, LTT).
RAID6/ZFS RAIDz2 is the way. Yes, you’re gonna lose quite a bit more space (leaving 24TB vs 32TB), but added reliability and peace of mind are priceless.
(And, in any case, make backups for anything critical! RAID is not a backup!)
They’re just nearly equally reactive in two opposite directions.
You can absolutely make salts with acidic or alkaline properties by altering this careful balance.
It’s like two titans fighting until both are dead and peace roams over the valley. Or, more accurately, relentless robber meeting someone who desperately needs to give something away.