A new compound has been shown to reverse late stage Alzheimer's disease in lab mice, which gives millions of sufferers new cause for hope.

In our latest attempts to make lab rats immortal, a new compound has been shown to reverse late stage Alzheimer’s disease in lab mice. This is a rare case where the title isn’t even clickbait.

  • gibmiser@lemmy.worldEnglish
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    7 months ago

    In a mouse model. The mice don’t have alzheimers they have… something we gave them that looks like it… Hopefully it is similar enough

    • Dr. Bob@lemmy.caEnglish
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      7 months ago

      We did something to the mice then rescued it in a different way. Hooray! Next we’ll save test tubes from cancer…again.

      • scarabic@lemmy.worldEnglish
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        7 months ago

        If you can’t get excited by incremental advancements, you should probably unsubscribe from science as a topic.

        • Dr. Bob@lemmy.caEnglish
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          7 months ago

          Dude it’s worse than that. I was a working neuroscientist for almost twenty years. So…jaded.

            • Dr. Bob@lemmy.caEnglish
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              7 months ago

              There is a lot of incremental research that gets transformed into ZOMG YOU GUYS!!! by the research office. The journals are full of papers demonstrating a complete rescue of a disease model ( and I’m an author on some of them). What the papers are really demonstrating is the inadequacy of the animal model.

        • azertyfun@sh.itjust.worksEnglish
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          7 months ago

          There are ways to do good, approachable, clickable science communication without resorting to lies, ommission, or exaggeration which is futurism.com’s whole schtick. There’s so much happening in science that doesn’t get covered by these low-quality sensationalist outlets because a misleading headline about petri dish cancer or mouse Alzheimer’s gets more clicks and requires far less research than an article about whatever interesting advancements actually happened in science this week.

          • scarabic@lemmy.worldEnglish
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            7 months ago

            I agree the field is full of subpar sensationalist coverage. I didn’t find this case so terrible as such things go. People in the thread were all freaking out about how “It’s not really Alzheimer’s, it’s something like Alzheimer’s which we did to the mice! Nothing to see here!”

            Which is an overreaction. On the one hand it should be obvious up front that mice cannot have actual human Alzheimer’s because they are fucking mice. So setting those semantics aside, something happened here, and people seemed disappointed that it wasn’t everything.

            So I think both of our points are valid here. Yes, coverage of science is terrible, but anyone who wants to follow science should be prepared for some very incremental advancements.

    • piconaut@lemmy.caEnglish
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      7 months ago

      Yeah, I didn’t read the whole thing but apparently only in 5xFAD mice. I wish they would have also tried it in a Tau model like PS19.

    • SaveTheTuaHawk@lemmy.caEnglish
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      7 months ago

      There has been a fucking epidemic of MD/scientists running to the media with miracle cures lately.

      Mice to not get Alzheimers, they were engineered to show one aspect of the disease that has been promoted by fraudulent studies. As for the reversal, mouse brains are highly plastic and similar to a human baby, nothing like a >60 year old.